Does TOFACITINIB Cause Intervertebral disc protrusion? 393 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 393 reports of Intervertebral disc protrusion have been filed in association with TOFACITINIB (XELJANZ XR). This represents 0.3% of all adverse event reports for TOFACITINIB.
393
Reports of Intervertebral disc protrusion with TOFACITINIB
0.3%
of all TOFACITINIB reports
6
Deaths
102
Hospitalizations
How Dangerous Is Intervertebral disc protrusion From TOFACITINIB?
Of the 393 reports, 6 (1.5%) resulted in death, 102 (26.0%) required hospitalization, and 2 (0.5%) were considered life-threatening.
Is Intervertebral disc protrusion Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOFACITINIB. However, 393 reports have been filed with the FAERS database.
What Other Side Effects Does TOFACITINIB Cause?
Drug ineffective (30,382)
Pain (21,659)
Condition aggravated (16,925)
Arthralgia (15,640)
Fatigue (13,551)
Rheumatoid arthritis (12,277)
Off label use (11,736)
Headache (11,061)
Joint swelling (10,686)
Malaise (9,040)
What Other Drugs Cause Intervertebral disc protrusion?
ADALIMUMAB (2,760)
ETANERCEPT (751)
METHOTREXATE (648)
SODIUM OXYBATE (427)
PREGABALIN (415)
UPADACITINIB (384)
INTERFERON BETA-1A (295)
PREDNISONE (285)
SECUKINUMAB (268)
ABATACEPT (257)
Which TOFACITINIB Alternatives Have Lower Intervertebral disc protrusion Risk?
TOFACITINIB vs TOFERSEN
TOFACITINIB vs TOLNAFTATE
TOFACITINIB vs TOLODODEKIN ALFA
TOFACITINIB vs TOLTERODINE
TOFACITINIB vs TOLVAPTAN