Intervertebral disc protrusion: Which Medications Cause It? (14,913 Reports Across 570 Drugs)
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Intervertebral disc protrusion has been reported as an adverse event with 570 different drugs in the FDA's FAERS database, with 14,913 total reports. 225 of these reports resulted in death.The drugs most commonly associated with Intervertebral disc protrusion are ADALIMUMAB, ETANERCEPT, and METHOTREXATE.
14,913
Total Reports
570
Drugs Involved
225
Deaths
6,155
Hospitalizations
56.7 yrs
Average Patient Age
68.3% / 31.7%
Female / Male
Which Drugs Cause Intervertebral disc protrusion Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| ADALIMUMAB | 2,760 | 0.6% | 3 | 1,169 | 6 |
| ETANERCEPT | 751 | 0.2% | 3 | 253 | 15 |
| METHOTREXATE | 648 | 0.3% | 12 | 338 | 17 |
| SODIUM OXYBATE | 427 | 0.7% | 0 | 83 | 0 |
| PREGABALIN | 415 | 0.4% | 2 | 143 | 29 |
| TOFACITINIB | 393 | 0.3% | 6 | 102 | 2 |
| UPADACITINIB | 384 | 0.6% | 1 | 144 | 1 |
| INTERFERON BETA-1A | 295 | 0.4% | 2 | 180 | 6 |
| PREDNISONE | 285 | 0.2% | 5 | 119 | 5 |
| SECUKINUMAB | 268 | 0.2% | 2 | 77 | 5 |
| ABATACEPT | 257 | 0.2% | 3 | 108 | 23 |
| RITUXIMAB | 235 | 0.1% | 12 | 152 | 11 |
| INFLIXIMAB | 233 | 0.2% | 0 | 91 | 1 |
| TOCILIZUMAB | 223 | 0.2% | 0 | 120 | 7 |
| NATALIZUMAB | 219 | 0.3% | 0 | 123 | 2 |
| OCRELIZUMAB | 217 | 0.4% | 2 | 98 | 3 |
| DIMETHYL | 216 | 0.2% | 0 | 127 | 2 |
| DENOSUMAB | 208 | 0.1% | 6 | 54 | 2 |
| RISANKIZUMAB-RZAA | 194 | 0.3% | 0 | 62 | 1 |
| ALENDRONATE | 183 | 0.7% | 6 | 167 | 1 |