Does TOFACITINIB Cause Joint stiffness? 1,819 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 1,819 reports of Joint stiffness have been filed in association with TOFACITINIB (XELJANZ XR). This represents 1.2% of all adverse event reports for TOFACITINIB.
1,819
Reports of Joint stiffness with TOFACITINIB
1.2%
of all TOFACITINIB reports
310
Deaths
355
Hospitalizations
How Dangerous Is Joint stiffness From TOFACITINIB?
Of the 1,819 reports, 310 (17.0%) resulted in death, 355 (19.5%) required hospitalization, and 219 (12.0%) were considered life-threatening.
Is Joint stiffness Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOFACITINIB. However, 1,819 reports have been filed with the FAERS database.
What Other Side Effects Does TOFACITINIB Cause?
Drug ineffective (30,382)
Pain (21,659)
Condition aggravated (16,925)
Arthralgia (15,640)
Fatigue (13,551)
Rheumatoid arthritis (12,277)
Off label use (11,736)
Headache (11,061)
Joint swelling (10,686)
Malaise (9,040)
What Other Drugs Cause Joint stiffness?
ADALIMUMAB (3,927)
ETANERCEPT (2,944)
METHOTREXATE (2,304)
TOCILIZUMAB (1,749)
ABATACEPT (1,385)
RITUXIMAB (1,366)
LEFLUNOMIDE (1,228)
HYDROXYCHLOROQUINE (1,206)
SULFASALAZINE (1,167)
SECUKINUMAB (1,138)
Which TOFACITINIB Alternatives Have Lower Joint stiffness Risk?
TOFACITINIB vs TOFERSEN
TOFACITINIB vs TOLNAFTATE
TOFACITINIB vs TOLODODEKIN ALFA
TOFACITINIB vs TOLTERODINE
TOFACITINIB vs TOLVAPTAN