Joint stiffness: Which Medications Cause It? (19,390 Reports Across 719 Drugs)
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Joint stiffness has been reported as an adverse event with 719 different drugs in the FDA's FAERS database, with 19,390 total reports. 722 of these reports resulted in death.The drugs most commonly associated with Joint stiffness are ADALIMUMAB, ETANERCEPT, and METHOTREXATE.
19,390
Total Reports
719
Drugs Involved
722
Deaths
3,135
Hospitalizations
55.1 yrs
Average Patient Age
71.2% / 28.8%
Female / Male
Which Drugs Cause Joint stiffness Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| ADALIMUMAB | 3,927 | 0.8% | 434 | 903 | 323 |
| ETANERCEPT | 2,944 | 0.8% | 334 | 446 | 250 |
| METHOTREXATE | 2,304 | 0.9% | 429 | 504 | 316 |
| TOFACITINIB | 1,819 | 1.2% | 310 | 355 | 219 |
| TOCILIZUMAB | 1,749 | 1.8% | 436 | 506 | 290 |
| ABATACEPT | 1,385 | 1.2% | 385 | 418 | 294 |
| RITUXIMAB | 1,366 | 0.8% | 366 | 513 | 321 |
| LEFLUNOMIDE | 1,228 | 2.2% | 304 | 391 | 297 |
| HYDROXYCHLOROQUINE | 1,206 | 1.8% | 369 | 362 | 269 |
| SULFASALAZINE | 1,167 | 2.9% | 384 | 363 | 270 |
| SECUKINUMAB | 1,138 | 0.8% | 307 | 373 | 303 |
| CERTOLIZUMAB PEGOL | 1,018 | 1.0% | 387 | 352 | 272 |
| INFLIXIMAB | 974 | 0.7% | 345 | 336 | 245 |
| GOLIMUMAB | 966 | 1.4% | 370 | 342 | 256 |
| PREDNISONE | 933 | 0.6% | 384 | 363 | 272 |
| APREMILAST | 779 | 0.6% | 360 | 233 | 227 |
| DICLOFENAC | 750 | 0.9% | 459 | 327 | 316 |
| DUPILUMAB | 646 | 0.2% | 0 | 23 | 1 |
| AZATHIOPRINE | 638 | 1.9% | 319 | 223 | 200 |
| FOLIC ACID | 623 | 2.7% | 392 | 295 | 271 |