Does APREMILAST Cause Joint stiffness? 779 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 779 reports of Joint stiffness have been filed in association with APREMILAST (Otezla). This represents 0.6% of all adverse event reports for APREMILAST.
779
Reports of Joint stiffness with APREMILAST
0.6%
of all APREMILAST reports
360
Deaths
233
Hospitalizations
How Dangerous Is Joint stiffness From APREMILAST?
Of the 779 reports, 360 (46.2%) resulted in death, 233 (29.9%) required hospitalization, and 227 (29.1%) were considered life-threatening.
Is Joint stiffness Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for APREMILAST. However, 779 reports have been filed with the FAERS database.
What Other Side Effects Does APREMILAST Cause?
Diarrhoea (23,752)
Nausea (21,352)
Psoriasis (19,255)
Headache (17,024)
Drug ineffective (14,121)
Abdominal discomfort (7,653)
Psoriatic arthropathy (7,035)
Vomiting (5,959)
Rash (5,883)
Pain (5,676)
What Other Drugs Cause Joint stiffness?
ADALIMUMAB (3,927)
ETANERCEPT (2,944)
METHOTREXATE (2,304)
TOFACITINIB (1,819)
TOCILIZUMAB (1,749)
ABATACEPT (1,385)
RITUXIMAB (1,366)
LEFLUNOMIDE (1,228)
HYDROXYCHLOROQUINE (1,206)
SULFASALAZINE (1,167)
Which APREMILAST Alternatives Have Lower Joint stiffness Risk?
APREMILAST vs APREPITANT
APREMILAST vs APROTININ
APREMILAST vs ARANESP
APREMILAST vs ARAVA
APREMILAST vs AREDIA