Does TOFACITINIB Cause Knee arthroplasty? 1,744 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 1,744 reports of Knee arthroplasty have been filed in association with TOFACITINIB (XELJANZ XR). This represents 1.1% of all adverse event reports for TOFACITINIB.
1,744
Reports of Knee arthroplasty with TOFACITINIB
1.1%
of all TOFACITINIB reports
464
Deaths
715
Hospitalizations
How Dangerous Is Knee arthroplasty From TOFACITINIB?
Of the 1,744 reports, 464 (26.6%) resulted in death, 715 (41.0%) required hospitalization, and 519 (29.8%) were considered life-threatening.
Is Knee arthroplasty Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOFACITINIB. However, 1,744 reports have been filed with the FAERS database.
What Other Side Effects Does TOFACITINIB Cause?
Drug ineffective (30,382)
Pain (21,659)
Condition aggravated (16,925)
Arthralgia (15,640)
Fatigue (13,551)
Rheumatoid arthritis (12,277)
Off label use (11,736)
Headache (11,061)
Joint swelling (10,686)
Malaise (9,040)
What Other Drugs Cause Knee arthroplasty?
ADALIMUMAB (3,627)
ETANERCEPT (3,541)
METHOTREXATE (2,311)
ABATACEPT (2,028)
TOCILIZUMAB (1,881)
HYDROXYCHLOROQUINE (1,828)
LEFLUNOMIDE (1,771)
INFLIXIMAB (1,751)
CERTOLIZUMAB PEGOL (1,731)
GOLIMUMAB (1,670)
Which TOFACITINIB Alternatives Have Lower Knee arthroplasty Risk?
TOFACITINIB vs TOFERSEN
TOFACITINIB vs TOLNAFTATE
TOFACITINIB vs TOLODODEKIN ALFA
TOFACITINIB vs TOLTERODINE
TOFACITINIB vs TOLVAPTAN