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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Does METHOTREXATE Cause Knee arthroplasty? 2,311 Reports in FDA Database

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According to the FDA Adverse Event Reporting System (FAERS), 2,311 reports of Knee arthroplasty have been filed in association with METHOTREXATE (Methotrexate). This represents 0.9% of all adverse event reports for METHOTREXATE.

2,311
Reports of Knee arthroplasty with METHOTREXATE
0.9%
of all METHOTREXATE reports
574
Deaths
884
Hospitalizations

How Dangerous Is Knee arthroplasty From METHOTREXATE?

Of the 2,311 reports, 574 (24.8%) resulted in death, 884 (38.3%) required hospitalization, and 629 (27.2%) were considered life-threatening.

Is Knee arthroplasty Listed in the Official Label?

This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 2,311 reports have been filed with the FAERS database.

What Other Side Effects Does METHOTREXATE Cause?

Drug ineffective (70,142) Rheumatoid arthritis (29,254) Off label use (24,020) Pain (23,773) Drug intolerance (22,555) Arthralgia (21,831) Fatigue (19,885) Nausea (18,715) Joint swelling (17,657) Drug hypersensitivity (16,677)

What Other Drugs Cause Knee arthroplasty?

ADALIMUMAB (3,627) ETANERCEPT (3,541) ABATACEPT (2,028) TOCILIZUMAB (1,881) HYDROXYCHLOROQUINE (1,828) LEFLUNOMIDE (1,771) INFLIXIMAB (1,751) TOFACITINIB (1,744) CERTOLIZUMAB PEGOL (1,731) GOLIMUMAB (1,670)

Which METHOTREXATE Alternatives Have Lower Knee arthroplasty Risk?

METHOTREXATE vs METHOXSALEN METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA METHOTREXATE vs METHYL ALCOHOL METHOTREXATE vs METHYLCOBALAMIN METHOTREXATE vs METHYLDOPA

Related Pages

METHOTREXATE Full Profile All Knee arthroplasty Reports All Drugs Causing Knee arthroplasty METHOTREXATE Demographics