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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Knee arthroplasty: Which Medications Cause It? (15,737 Reports Across 517 Drugs)

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Knee arthroplasty has been reported as an adverse event with 517 different drugs in the FDA's FAERS database, with 15,737 total reports. 864 of these reports resulted in death.The drugs most commonly associated with Knee arthroplasty are ADALIMUMAB, ETANERCEPT, and METHOTREXATE.

15,737
Total Reports
517
Drugs Involved
864
Deaths
5,794
Hospitalizations
62.9 yrs
Average Patient Age
74.3% / 25.7%
Female / Male

Which Drugs Cause Knee arthroplasty Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
ADALIMUMAB 3,627 0.7% 574 1,251 594
ETANERCEPT 3,541 1.0% 473 1,199 524
METHOTREXATE 2,311 0.9% 574 884 629
ABATACEPT 2,028 1.8% 515 699 555
TOCILIZUMAB 1,881 1.9% 580 670 585
HYDROXYCHLOROQUINE 1,828 2.7% 538 641 579
LEFLUNOMIDE 1,771 3.1% 466 675 579
INFLIXIMAB 1,751 1.3% 506 623 554
TOFACITINIB 1,744 1.1% 464 715 519
CERTOLIZUMAB PEGOL 1,731 1.8% 507 594 520
GOLIMUMAB 1,670 2.4% 501 592 517
RITUXIMAB 1,660 0.9% 503 671 583
ALENDRONATE 1,605 5.8% 535 736 542
SULFASALAZINE 1,531 3.8% 524 624 561
PREDNISONE 1,524 1.0% 512 587 541
FOLIC ACID 1,422 6.2% 543 545 561
CETIRIZINE 1,344 2.8% 522 529 540
PHTHALYLSULFATHIAZOLE 1,269 13.6% 471 490 503
DICLOFENAC 1,257 1.5% 543 552 547
DESOXIMETASONE 1,181 10.2% 526 498 542

View all 517 drugs →

Top 3 Drugs Associated With Knee arthroplasty

3,627 reports
3,541 reports
2,311 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)