Does TOFACITINIB Cause Toe amputation? 21 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 21 reports of Toe amputation have been filed in association with TOFACITINIB (XELJANZ XR). This represents 0.0% of all adverse event reports for TOFACITINIB.
21
Reports of Toe amputation with TOFACITINIB
0.0%
of all TOFACITINIB reports
2
Deaths
9
Hospitalizations
How Dangerous Is Toe amputation From TOFACITINIB?
Of the 21 reports, 2 (9.5%) resulted in death, 9 (42.9%) required hospitalization, and 1 (4.8%) were considered life-threatening.
Is Toe amputation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOFACITINIB. However, 21 reports have been filed with the FAERS database.
What Other Side Effects Does TOFACITINIB Cause?
Drug ineffective (30,382)
Pain (21,659)
Condition aggravated (16,925)
Arthralgia (15,640)
Fatigue (13,551)
Rheumatoid arthritis (12,277)
Off label use (11,736)
Headache (11,061)
Joint swelling (10,686)
Malaise (9,040)
What Other Drugs Cause Toe amputation?
CANAGLIFLOZIN (2,193)
CANAGLIFLOZIN\METFORMIN (196)
EMPAGLIFLOZIN (149)
INSULIN GLARGINE (133)
ADALIMUMAB (124)
METFORMIN (103)
BECAPLERMIN (102)
ETANERCEPT (100)
METHOTREXATE (84)
TOCILIZUMAB (66)
Which TOFACITINIB Alternatives Have Lower Toe amputation Risk?
TOFACITINIB vs TOFERSEN
TOFACITINIB vs TOLNAFTATE
TOFACITINIB vs TOLODODEKIN ALFA
TOFACITINIB vs TOLTERODINE
TOFACITINIB vs TOLVAPTAN