Does TOLVAPTAN Cause Hyponatraemia? 178 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 178 reports of Hyponatraemia have been filed in association with TOLVAPTAN (Jynarque). This represents 2.0% of all adverse event reports for TOLVAPTAN.
178
Reports of Hyponatraemia with TOLVAPTAN
2.0%
of all TOLVAPTAN reports
16
Deaths
107
Hospitalizations
How Dangerous Is Hyponatraemia From TOLVAPTAN?
Of the 178 reports, 16 (9.0%) resulted in death, 107 (60.1%) required hospitalization, and 7 (3.9%) were considered life-threatening.
Is Hyponatraemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOLVAPTAN. However, 178 reports have been filed with the FAERS database.
What Other Side Effects Does TOLVAPTAN Cause?
Death (800)
Thirst (624)
Off label use (560)
Renal impairment (534)
Underdose (448)
Product use in unapproved indication (446)
Wrong technique in product usage process (426)
Polyuria (390)
Product dose omission issue (379)
Inappropriate schedule of product administration (376)
What Other Drugs Cause Hyponatraemia?
FUROSEMIDE (3,127)
HYDROCHLOROTHIAZIDE (2,138)
OMEPRAZOLE (1,635)
LANSOPRAZOLE (1,416)
SERTRALINE (1,332)
RAMIPRIL (1,178)
SPIRONOLACTONE (1,166)
PANTOPRAZOLE (1,134)
INDAPAMIDE (976)
AMLODIPINE (879)
Which TOLVAPTAN Alternatives Have Lower Hyponatraemia Risk?
TOLVAPTAN vs TOPAMAX
TOLVAPTAN vs TOPIRAMATE
TOLVAPTAN vs TOPOTECAN
TOLVAPTAN vs TOPOTECAN\TOPOTECAN
TOLVAPTAN vs TOPROL