Does TOLVAPTAN Cause Pancytopenia? 34 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 34 reports of Pancytopenia have been filed in association with TOLVAPTAN (Jynarque). This represents 0.4% of all adverse event reports for TOLVAPTAN.
34
Reports of Pancytopenia with TOLVAPTAN
0.4%
of all TOLVAPTAN reports
5
Deaths
9
Hospitalizations
How Dangerous Is Pancytopenia From TOLVAPTAN?
Of the 34 reports, 5 (14.7%) resulted in death, 9 (26.5%) required hospitalization, and 1 (2.9%) were considered life-threatening.
Is Pancytopenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOLVAPTAN. However, 34 reports have been filed with the FAERS database.
What Other Side Effects Does TOLVAPTAN Cause?
Death (800)
Thirst (624)
Off label use (560)
Renal impairment (534)
Underdose (448)
Product use in unapproved indication (446)
Wrong technique in product usage process (426)
Polyuria (390)
Product dose omission issue (379)
Inappropriate schedule of product administration (376)
What Other Drugs Cause Pancytopenia?
METHOTREXATE (5,377)
CYCLOPHOSPHAMIDE (3,351)
CARBOPLATIN (2,910)
RITUXIMAB (2,400)
LENALIDOMIDE (2,259)
DOXORUBICIN (2,212)
VINCRISTINE (2,180)
ETOPOSIDE (2,129)
DEXAMETHASONE (2,053)
PREDNISONE (1,743)
Which TOLVAPTAN Alternatives Have Lower Pancytopenia Risk?
TOLVAPTAN vs TOPAMAX
TOLVAPTAN vs TOPIRAMATE
TOLVAPTAN vs TOPOTECAN
TOLVAPTAN vs TOPOTECAN\TOPOTECAN
TOLVAPTAN vs TOPROL