TOPIRAMATE for Epilepsy: Side Effects & Safety Data
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There are 2,828 adverse event reports in the FDA FAERS database where TOPIRAMATE was used for Epilepsy.
Most Reported Side Effects for TOPIRAMATE
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Drug ineffective | 5,553 | 19.4% | 642 | 1,391 |
| Off label use | 4,248 | 14.9% | 932 | 1,409 |
| Product use in unapproved indication | 2,173 | 7.6% | 579 | 752 |
| Headache | 1,997 | 7.0% | 416 | 697 |
| Drug intolerance | 1,820 | 6.4% | 533 | 549 |
| Migraine | 1,796 | 6.3% | 371 | 558 |
| Nausea | 1,691 | 5.9% | 420 | 597 |
| Seizure | 1,535 | 5.4% | 44 | 447 |
| Paraesthesia | 1,506 | 5.3% | 431 | 538 |
| Dizziness | 1,466 | 5.1% | 414 | 534 |
| Fatigue | 1,423 | 5.0% | 423 | 606 |
| Product use issue | 1,345 | 4.7% | 366 | 425 |
| Pain | 1,254 | 4.4% | 578 | 637 |
| Vomiting | 1,212 | 4.2% | 515 | 676 |
| Depression | 1,182 | 4.1% | 456 | 551 |
Other Indications for TOPIRAMATE
Product used for unknown indication (8,128)
Migraine (5,515)
Seizure (1,931)
Migraine prophylaxis (1,227)
Headache (709)
Partial seizures (534)
Status epilepticus (454)
Generalised tonic-clonic seizure (361)
Weight decreased (251)
Bipolar disorder (231)
Other Drugs Used for Epilepsy
LEVETIRACETAM (17,599)
LAMOTRIGINE (8,886)
LACOSAMIDE (5,941)
CANNABIDIOL (5,555)
CARBAMAZEPINE (4,329)
VALPROATE (3,697)
VALPROIC ACID (3,229)
VIGABATRIN (2,896)
CLOBAZAM (2,840)
PHENYTOIN (2,376)