Does TOPIRAMATE Cause Depression? 1,182 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 1,182 reports of Depression have been filed in association with TOPIRAMATE (Topiramate). This represents 4.1% of all adverse event reports for TOPIRAMATE.
1,182
Reports of Depression with TOPIRAMATE
4.1%
of all TOPIRAMATE reports
456
Deaths
551
Hospitalizations
How Dangerous Is Depression From TOPIRAMATE?
Of the 1,182 reports, 456 (38.6%) resulted in death, 551 (46.6%) required hospitalization, and 484 (40.9%) were considered life-threatening.
Is Depression Listed in the Official Label?
Yes, Depression is listed as a known adverse reaction in the official FDA drug label for TOPIRAMATE.
What Other Side Effects Does TOPIRAMATE Cause?
Drug ineffective (5,553)
Off label use (4,248)
Product use in unapproved indication (2,173)
Headache (1,997)
Drug intolerance (1,820)
Migraine (1,796)
Nausea (1,691)
Seizure (1,535)
Paraesthesia (1,506)
Dizziness (1,466)
What Other Drugs Cause Depression?
OXYCODONE (6,871)
ADALIMUMAB (6,340)
APREMILAST (5,129)
ACETAMINOPHEN\OXYCODONE (4,035)
ACETAMINOPHEN\HYDROCODONE (3,699)
METHOTREXATE (3,577)
ETANERCEPT (3,538)
LEVONORGESTREL (3,529)
MORPHINE (3,280)
PREDNISONE (3,211)
Which TOPIRAMATE Alternatives Have Lower Depression Risk?
TOPIRAMATE vs TOPOTECAN
TOPIRAMATE vs TOPOTECAN\TOPOTECAN
TOPIRAMATE vs TOPROL
TOPIRAMATE vs TOREMIFENE
TOPIRAMATE vs TORIPALIMAB