Does TOPIRAMATE Cause Hepatitis? 328 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 328 reports of Hepatitis have been filed in association with TOPIRAMATE (Topiramate). This represents 1.2% of all adverse event reports for TOPIRAMATE.
328
Reports of Hepatitis with TOPIRAMATE
1.2%
of all TOPIRAMATE reports
295
Deaths
307
Hospitalizations
How Dangerous Is Hepatitis From TOPIRAMATE?
Of the 328 reports, 295 (89.9%) resulted in death, 307 (93.6%) required hospitalization, and 293 (89.3%) were considered life-threatening.
Is Hepatitis Listed in the Official Label?
Yes, Hepatitis is listed as a known adverse reaction in the official FDA drug label for TOPIRAMATE.
What Other Side Effects Does TOPIRAMATE Cause?
Drug ineffective (5,553)
Off label use (4,248)
Product use in unapproved indication (2,173)
Headache (1,997)
Drug intolerance (1,820)
Migraine (1,796)
Nausea (1,691)
Seizure (1,535)
Paraesthesia (1,506)
Dizziness (1,466)
What Other Drugs Cause Hepatitis?
METHOTREXATE (1,835)
ACETAMINOPHEN (1,450)
TOCILIZUMAB (1,184)
HYDROXYCHLOROQUINE (1,133)
ADALIMUMAB (1,096)
RITUXIMAB (1,017)
ETANERCEPT (1,013)
LEFLUNOMIDE (997)
PEMBROLIZUMAB (935)
NIVOLUMAB (930)
Which TOPIRAMATE Alternatives Have Lower Hepatitis Risk?
TOPIRAMATE vs TOPOTECAN
TOPIRAMATE vs TOPOTECAN\TOPOTECAN
TOPIRAMATE vs TOPROL
TOPIRAMATE vs TOREMIFENE
TOPIRAMATE vs TORIPALIMAB