Does TOPIRAMATE Cause Hyperammonaemic encephalopathy? 101 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 101 reports of Hyperammonaemic encephalopathy have been filed in association with TOPIRAMATE (Topiramate). This represents 0.4% of all adverse event reports for TOPIRAMATE.
101
Reports of Hyperammonaemic encephalopathy with TOPIRAMATE
0.4%
of all TOPIRAMATE reports
0
Deaths
73
Hospitalizations
How Dangerous Is Hyperammonaemic encephalopathy From TOPIRAMATE?
Of the 101 reports, 73 (72.3%) required hospitalization, and 5 (5.0%) were considered life-threatening.
Is Hyperammonaemic encephalopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOPIRAMATE. However, 101 reports have been filed with the FAERS database.
What Other Side Effects Does TOPIRAMATE Cause?
Drug ineffective (5,553)
Off label use (4,248)
Product use in unapproved indication (2,173)
Headache (1,997)
Drug intolerance (1,820)
Migraine (1,796)
Nausea (1,691)
Seizure (1,535)
Paraesthesia (1,506)
Dizziness (1,466)
What Other Drugs Cause Hyperammonaemic encephalopathy?
VALPROIC ACID (455)
FLUOROURACIL (156)
VALPROATE (120)
DIVALPROEX (119)
OXALIPLATIN (107)
RISPERIDONE (96)
QUETIAPINE (91)
LEVETIRACETAM (71)
LEUCOVORIN (62)
CAPECITABINE (60)
Which TOPIRAMATE Alternatives Have Lower Hyperammonaemic encephalopathy Risk?
TOPIRAMATE vs TOPOTECAN
TOPIRAMATE vs TOPOTECAN\TOPOTECAN
TOPIRAMATE vs TOPROL
TOPIRAMATE vs TOREMIFENE
TOPIRAMATE vs TORIPALIMAB