Does FLUOROURACIL Cause Hyperammonaemic encephalopathy? 156 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 156 reports of Hyperammonaemic encephalopathy have been filed in association with FLUOROURACIL (FLUOROURACIL). This represents 0.3% of all adverse event reports for FLUOROURACIL.
156
Reports of Hyperammonaemic encephalopathy with FLUOROURACIL
0.3%
of all FLUOROURACIL reports
11
Deaths
81
Hospitalizations
How Dangerous Is Hyperammonaemic encephalopathy From FLUOROURACIL?
Of the 156 reports, 11 (7.1%) resulted in death, 81 (51.9%) required hospitalization, and 39 (25.0%) were considered life-threatening.
Is Hyperammonaemic encephalopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for FLUOROURACIL. However, 156 reports have been filed with the FAERS database.
What Other Side Effects Does FLUOROURACIL Cause?
Diarrhoea (5,373)
Neutropenia (4,400)
Nausea (3,757)
Vomiting (2,836)
Off label use (2,788)
Neuropathy peripheral (2,605)
Thrombocytopenia (2,426)
Fatigue (2,421)
Disease progression (2,377)
Febrile neutropenia (2,230)
What Other Drugs Cause Hyperammonaemic encephalopathy?
VALPROIC ACID (455)
VALPROATE (120)
DIVALPROEX (119)
OXALIPLATIN (107)
TOPIRAMATE (101)
RISPERIDONE (96)
QUETIAPINE (91)
LEVETIRACETAM (71)
LEUCOVORIN (62)
CAPECITABINE (60)
Which FLUOROURACIL Alternatives Have Lower Hyperammonaemic encephalopathy Risk?
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOROURACIL\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOXETINE
FLUOROURACIL vs FLUOXETINE\FLUOXETINE