Does TOPIRAMATE Cause Mitochondrial dna mutation? 33 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 33 reports of Mitochondrial dna mutation have been filed in association with TOPIRAMATE (Topiramate). This represents 0.1% of all adverse event reports for TOPIRAMATE.
33
Reports of Mitochondrial dna mutation with TOPIRAMATE
0.1%
of all TOPIRAMATE reports
33
Deaths
26
Hospitalizations
How Dangerous Is Mitochondrial dna mutation From TOPIRAMATE?
Of the 33 reports, 33 (100.0%) resulted in death, 26 (78.8%) required hospitalization, and 21 (63.6%) were considered life-threatening.
Is Mitochondrial dna mutation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOPIRAMATE. However, 33 reports have been filed with the FAERS database.
What Other Side Effects Does TOPIRAMATE Cause?
Drug ineffective (5,553)
Off label use (4,248)
Product use in unapproved indication (2,173)
Headache (1,997)
Drug intolerance (1,820)
Migraine (1,796)
Nausea (1,691)
Seizure (1,535)
Paraesthesia (1,506)
Dizziness (1,466)
What Other Drugs Cause Mitochondrial dna mutation?
VALPROIC ACID (38)
LACOSAMIDE (35)
LEVETIRACETAM (35)
PROPOFOL (34)
DEXAMETHASONE (33)
ISOFLURANE (33)
KETAMINE (33)
MIDAZOLAM (33)
PENTOBARBITAL (33)
CLOBAZAM (32)
Which TOPIRAMATE Alternatives Have Lower Mitochondrial dna mutation Risk?
TOPIRAMATE vs TOPOTECAN
TOPIRAMATE vs TOPOTECAN\TOPOTECAN
TOPIRAMATE vs TOPROL
TOPIRAMATE vs TOREMIFENE
TOPIRAMATE vs TORIPALIMAB