Does ISOFLURANE Cause Mitochondrial dna mutation? 33 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 33 reports of Mitochondrial dna mutation have been filed in association with ISOFLURANE (Isoflurane). This represents 4.0% of all adverse event reports for ISOFLURANE.
33
Reports of Mitochondrial dna mutation with ISOFLURANE
4.0%
of all ISOFLURANE reports
33
Deaths
26
Hospitalizations
How Dangerous Is Mitochondrial dna mutation From ISOFLURANE?
Of the 33 reports, 33 (100.0%) resulted in death, 26 (78.8%) required hospitalization, and 21 (63.6%) were considered life-threatening.
Is Mitochondrial dna mutation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ISOFLURANE. However, 33 reports have been filed with the FAERS database.
What Other Side Effects Does ISOFLURANE Cause?
Drug ineffective (134)
Hypotension (127)
Off label use (90)
Hyperthermia malignant (87)
Intestinal ischaemia (77)
Status epilepticus (75)
Systemic inflammatory response syndrome (63)
Necrosis ischaemic (56)
Post procedural complication (55)
Metabolic acidosis (54)
What Other Drugs Cause Mitochondrial dna mutation?
VALPROIC ACID (38)
LACOSAMIDE (35)
LEVETIRACETAM (35)
PROPOFOL (34)
DEXAMETHASONE (33)
KETAMINE (33)
MIDAZOLAM (33)
PENTOBARBITAL (33)
TOPIRAMATE (33)
CLOBAZAM (32)
Which ISOFLURANE Alternatives Have Lower Mitochondrial dna mutation Risk?
ISOFLURANE vs ISONIAZID
ISOFLURANE vs ISONIAZID\PYRAZINAMIDE\RIFAMPIN
ISOFLURANE vs ISONIAZID\PYRIDOXINE\SULFAMETHOXAZOLE\TRIMETHOPRIM
ISOFLURANE vs ISONIAZID\RIFAMPIN
ISOFLURANE vs ISOPROPANOLAMINE