Does TOPIRAMATE Cause Musculoskeletal stiffness? 469 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 469 reports of Musculoskeletal stiffness have been filed in association with TOPIRAMATE (Topiramate). This represents 1.6% of all adverse event reports for TOPIRAMATE.
469
Reports of Musculoskeletal stiffness with TOPIRAMATE
1.6%
of all TOPIRAMATE reports
348
Deaths
367
Hospitalizations
How Dangerous Is Musculoskeletal stiffness From TOPIRAMATE?
Of the 469 reports, 348 (74.2%) resulted in death, 367 (78.3%) required hospitalization, and 355 (75.7%) were considered life-threatening.
Is Musculoskeletal stiffness Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOPIRAMATE. However, 469 reports have been filed with the FAERS database.
What Other Side Effects Does TOPIRAMATE Cause?
Drug ineffective (5,553)
Off label use (4,248)
Product use in unapproved indication (2,173)
Headache (1,997)
Drug intolerance (1,820)
Migraine (1,796)
Nausea (1,691)
Seizure (1,535)
Paraesthesia (1,506)
Dizziness (1,466)
What Other Drugs Cause Musculoskeletal stiffness?
ADALIMUMAB (10,762)
METHOTREXATE (9,903)
ETANERCEPT (9,744)
TOFACITINIB (7,354)
TOCILIZUMAB (6,346)
RITUXIMAB (6,058)
LEFLUNOMIDE (6,031)
ABATACEPT (5,926)
SECUKINUMAB (5,655)
HYDROXYCHLOROQUINE (5,271)
Which TOPIRAMATE Alternatives Have Lower Musculoskeletal stiffness Risk?
TOPIRAMATE vs TOPOTECAN
TOPIRAMATE vs TOPOTECAN\TOPOTECAN
TOPIRAMATE vs TOPROL
TOPIRAMATE vs TOREMIFENE
TOPIRAMATE vs TORIPALIMAB