TOPOTECAN for Refractory cancer: Side Effects & Safety Data
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There are 141 adverse event reports in the FDA FAERS database where TOPOTECAN was used for Refractory cancer.
Most Reported Side Effects for TOPOTECAN
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Febrile neutropenia | 425 | 12.0% | 21 | 330 |
| Off label use | 390 | 11.0% | 88 | 72 |
| Death | 332 | 9.4% | 331 | 17 |
| Product use in unapproved indication | 323 | 9.1% | 36 | 40 |
| Neutropenia | 255 | 7.2% | 34 | 147 |
| Pyrexia | 252 | 7.1% | 23 | 222 |
| Anaemia | 242 | 6.8% | 35 | 125 |
| Malignant neoplasm progression | 238 | 6.7% | 61 | 26 |
| Drug ineffective | 216 | 6.1% | 56 | 30 |
| Disease progression | 207 | 5.9% | 77 | 30 |
| Thrombocytopenia | 207 | 5.9% | 39 | 79 |
| Vomiting | 206 | 5.8% | 16 | 135 |
| Pancytopenia | 177 | 5.0% | 32 | 99 |
| Diarrhoea | 168 | 4.8% | 13 | 111 |
| Nausea | 163 | 4.6% | 19 | 70 |
Other Indications for TOPOTECAN
Neuroblastoma (443)
Product used for unknown indication (350)
Retinoblastoma (302)
Lung neoplasm malignant (177)
Small cell lung cancer (158)
Ovarian cancer (155)
Recurrent cancer (114)
Neoplasm malignant (86)
Congenital retinoblastoma (83)
Chemotherapy (79)
Other Drugs Used for Refractory cancer
VENETOCLAX (177)
CYCLOPHOSPHAMIDE (168)
DOXORUBICIN (33)
AZACITIDINE (25)
DEXAMETHASONE (23)
VINCRISTINE (17)
ETOPOSIDE (12)
CYTARABINE (11)
PEGFILGRASTIM (10)
IFOSFAMIDE (8)