Does TOPOTECAN Cause Myelodysplastic syndrome? 44 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 44 reports of Myelodysplastic syndrome have been filed in association with TOPOTECAN (HYCAMTIN). This represents 1.2% of all adverse event reports for TOPOTECAN.
44
Reports of Myelodysplastic syndrome with TOPOTECAN
1.2%
of all TOPOTECAN reports
12
Deaths
8
Hospitalizations
How Dangerous Is Myelodysplastic syndrome From TOPOTECAN?
Of the 44 reports, 12 (27.3%) resulted in death, 8 (18.2%) required hospitalization, and 5 (11.4%) were considered life-threatening.
Is Myelodysplastic syndrome Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOPOTECAN. However, 44 reports have been filed with the FAERS database.
What Other Side Effects Does TOPOTECAN Cause?
Febrile neutropenia (425)
Off label use (390)
Death (332)
Product use in unapproved indication (323)
Neutropenia (255)
Pyrexia (252)
Anaemia (242)
Malignant neoplasm progression (238)
Drug ineffective (216)
Disease progression (207)
What Other Drugs Cause Myelodysplastic syndrome?
CYCLOPHOSPHAMIDE (1,545)
LENALIDOMIDE (1,285)
DOXORUBICIN (1,236)
RITUXIMAB (1,054)
VINCRISTINE (966)
ETOPOSIDE (936)
DEXAMETHASONE (759)
METHOTREXATE (728)
CYTARABINE (715)
CARBOPLATIN (698)
Which TOPOTECAN Alternatives Have Lower Myelodysplastic syndrome Risk?
TOPOTECAN vs TOPOTECAN\TOPOTECAN
TOPOTECAN vs TOPROL
TOPOTECAN vs TOREMIFENE
TOPOTECAN vs TORIPALIMAB
TOPOTECAN vs TORSEMIDE