Does TRAMADOL Cause Cholestasis? 305 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 305 reports of Cholestasis have been filed in association with TRAMADOL (ConZip). This represents 0.4% of all adverse event reports for TRAMADOL.
305
Reports of Cholestasis with TRAMADOL
0.4%
of all TRAMADOL reports
11
Deaths
188
Hospitalizations
How Dangerous Is Cholestasis From TRAMADOL?
Of the 305 reports, 11 (3.6%) resulted in death, 188 (61.6%) required hospitalization, and 22 (7.2%) were considered life-threatening.
Is Cholestasis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TRAMADOL. However, 305 reports have been filed with the FAERS database.
What Other Side Effects Does TRAMADOL Cause?
Drug dependence (21,018)
Overdose (12,705)
Dependence (8,530)
Pain (7,758)
Toxicity to various agents (5,252)
Emotional distress (4,901)
Drug abuse (4,553)
Vomiting (4,396)
Drug hypersensitivity (4,052)
Death (4,012)
What Other Drugs Cause Cholestasis?
ACETAMINOPHEN (1,269)
ATORVASTATIN (898)
PANTOPRAZOLE (535)
METHOTREXATE (507)
AMOXICILLIN\CLAVULANATE (480)
SULFAMETHOXAZOLE\TRIMETHOPRIM (462)
ENOXAPARIN (404)
PIPERACILLIN\TAZOBACTAM (394)
ESOMEPRAZOLE (363)
NIVOLUMAB (342)
Which TRAMADOL Alternatives Have Lower Cholestasis Risk?
TRAMADOL vs TRAMADOL\TRAMADOL
TRAMADOL vs TRAMETINIB
TRAMADOL vs TRAMETINIB DIMETHYL SULFOXIDE
TRAMADOL vs TRANDOLAPRIL
TRAMADOL vs TRANDOLAPRIL\VERAPAMIL