Does TRAMETINIB DIMETHYL SULFOXIDE Cause Off label use? 339 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 339 reports of Off label use have been filed in association with TRAMETINIB DIMETHYL SULFOXIDE (Mekinist). This represents 2.1% of all adverse event reports for TRAMETINIB DIMETHYL SULFOXIDE.
339
Reports of Off label use with TRAMETINIB DIMETHYL SULFOXIDE
2.1%
of all TRAMETINIB DIMETHYL SULFOXIDE reports
29
Deaths
42
Hospitalizations
How Dangerous Is Off label use From TRAMETINIB DIMETHYL SULFOXIDE?
Of the 339 reports, 29 (8.6%) resulted in death, 42 (12.4%) required hospitalization, and 4 (1.2%) were considered life-threatening.
Is Off label use Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TRAMETINIB DIMETHYL SULFOXIDE. However, 339 reports have been filed with the FAERS database.
What Other Side Effects Does TRAMETINIB DIMETHYL SULFOXIDE Cause?
Death (2,998)
Pyrexia (2,660)
Rash (1,271)
Fatigue (1,143)
Malignant neoplasm progression (1,114)
Nausea (1,085)
Chills (965)
Diarrhoea (867)
Vomiting (720)
Product use in unapproved indication (687)
What Other Drugs Cause Off label use?
RITUXIMAB (39,751)
INFLIXIMAB (34,801)
DENOSUMAB (34,612)
METHOTREXATE (24,020)
VEDOLIZUMAB (21,017)
ETANERCEPT (20,178)
TOCILIZUMAB (18,256)
PREDNISONE (17,867)
LENALIDOMIDE (17,017)
ADALIMUMAB (16,417)
Which TRAMETINIB DIMETHYL SULFOXIDE Alternatives Have Lower Off label use Risk?
TRAMETINIB DIMETHYL SULFOXIDE vs TRANDOLAPRIL
TRAMETINIB DIMETHYL SULFOXIDE vs TRANDOLAPRIL\VERAPAMIL
TRAMETINIB DIMETHYL SULFOXIDE vs TRANEXAMIC ACID
TRAMETINIB DIMETHYL SULFOXIDE vs TRANYLCYPROMINE
TRAMETINIB DIMETHYL SULFOXIDE vs TRASTUZUMAB