TRASTUZUMAB DERUXTECAN for Prophylaxis: Side Effects & Safety Data
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There are 7 adverse event reports in the FDA FAERS database where TRASTUZUMAB DERUXTECAN was used for Prophylaxis.
Most Reported Side Effects for TRASTUZUMAB DERUXTECAN
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Death | 384 | 14.3% | 384 | 24 |
| Off label use | 258 | 9.6% | 36 | 71 |
| Nausea | 251 | 9.4% | 18 | 86 |
| Myelosuppression | 242 | 9.0% | 0 | 98 |
| Fatigue | 186 | 6.9% | 14 | 61 |
| Malignant neoplasm progression | 171 | 6.4% | 48 | 29 |
| Vomiting | 140 | 5.2% | 20 | 58 |
| Diarrhoea | 132 | 4.9% | 23 | 68 |
| Interstitial lung disease | 130 | 4.8% | 46 | 46 |
| Pneumonitis | 125 | 4.7% | 41 | 48 |
| Metastases to central nervous system | 103 | 3.8% | 22 | 25 |
| Toxicity to various agents | 97 | 3.6% | 2 | 15 |
| Asthenia | 95 | 3.5% | 13 | 40 |
| Disease progression | 87 | 3.2% | 29 | 14 |
| Dyspnoea | 77 | 2.9% | 23 | 38 |
Other Indications for TRASTUZUMAB DERUXTECAN
Her2 positive breast cancer (768)
Breast cancer metastatic (503)
Breast cancer (378)
Product used for unknown indication (362)
Her2 low breast cancer (110)
Breast cancer female (78)
Her2 negative breast cancer (57)
Chemotherapy (48)
Neoplasm (43)
Gastric cancer (37)
Other Drugs Used for Prophylaxis
PEGFILGRASTIM (7,424)
HUMAN C1-ESTERASE INHIBITOR (5,950)
DENOSUMAB (4,541)
SULFAMETHOXAZOLE\TRIMETHOPRIM (3,197)
ASPIRIN (2,083)
VALACYCLOVIR (1,574)
PANTOPRAZOLE (1,502)
VARICELLA-ZOSTER VIRUS STRAIN OKA/MERCK LIVE ANTIGEN (1,444)
CLOPIDOGREL BISULFATE (1,296)
ENOXAPARIN (1,278)