Does TRASTUZUMAB DERUXTECAN Cause Off label use? 258 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 258 reports of Off label use have been filed in association with TRASTUZUMAB DERUXTECAN (Enhertu). This represents 9.6% of all adverse event reports for TRASTUZUMAB DERUXTECAN.
258
Reports of Off label use with TRASTUZUMAB DERUXTECAN
9.6%
of all TRASTUZUMAB DERUXTECAN reports
36
Deaths
71
Hospitalizations
How Dangerous Is Off label use From TRASTUZUMAB DERUXTECAN?
Of the 258 reports, 36 (14.0%) resulted in death, 71 (27.5%) required hospitalization, and 6 (2.3%) were considered life-threatening.
Is Off label use Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TRASTUZUMAB DERUXTECAN. However, 258 reports have been filed with the FAERS database.
What Other Side Effects Does TRASTUZUMAB DERUXTECAN Cause?
Death (384)
Nausea (251)
Myelosuppression (242)
Fatigue (186)
Malignant neoplasm progression (171)
Vomiting (140)
Diarrhoea (132)
Interstitial lung disease (130)
Pneumonitis (125)
Metastases to central nervous system (103)
What Other Drugs Cause Off label use?
RITUXIMAB (39,751)
INFLIXIMAB (34,801)
DENOSUMAB (34,612)
METHOTREXATE (24,020)
VEDOLIZUMAB (21,017)
ETANERCEPT (20,178)
TOCILIZUMAB (18,256)
PREDNISONE (17,867)
LENALIDOMIDE (17,017)
ADALIMUMAB (16,417)
Which TRASTUZUMAB DERUXTECAN Alternatives Have Lower Off label use Risk?
TRASTUZUMAB DERUXTECAN vs TRASTUZUMAB-DKST
TRASTUZUMAB DERUXTECAN vs TRASTUZUMAB-DTTB
TRASTUZUMAB DERUXTECAN vs TRASTUZUMAB EMTANSINE
TRASTUZUMAB DERUXTECAN vs TRASTUZUMAB-PKRB
TRASTUZUMAB DERUXTECAN vs TRASTUZUMAB-QYYP