Does TRASTUZUMAB Cause Clostridium difficile colitis? 42 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 42 reports of Clostridium difficile colitis have been filed in association with TRASTUZUMAB (Trazimera). This represents 0.1% of all adverse event reports for TRASTUZUMAB.
42
Reports of Clostridium difficile colitis with TRASTUZUMAB
0.1%
of all TRASTUZUMAB reports
14
Deaths
34
Hospitalizations
How Dangerous Is Clostridium difficile colitis From TRASTUZUMAB?
Of the 42 reports, 14 (33.3%) resulted in death, 34 (81.0%) required hospitalization, and 2 (4.8%) were considered life-threatening.
Is Clostridium difficile colitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TRASTUZUMAB. However, 42 reports have been filed with the FAERS database.
What Other Side Effects Does TRASTUZUMAB Cause?
Diarrhoea (4,996)
Off label use (3,802)
Nausea (3,499)
Fatigue (3,417)
Myelosuppression (2,552)
Disease progression (2,449)
Death (2,378)
Vomiting (2,244)
Dyspnoea (2,010)
Pyrexia (1,886)
What Other Drugs Cause Clostridium difficile colitis?
CYCLOPHOSPHAMIDE (717)
PREDNISONE (619)
DEXAMETHASONE (575)
METHOTREXATE (562)
ETOPOSIDE (503)
CYTARABINE (489)
VINCRISTINE (482)
LENALIDOMIDE (388)
METHYLPREDNISOLONE (385)
CIPROFLOXACIN (378)
Which TRASTUZUMAB Alternatives Have Lower Clostridium difficile colitis Risk?
TRASTUZUMAB vs TRASTUZUMAB-ANNS
TRASTUZUMAB vs TRASTUZUMAB DERUXTECAN
TRASTUZUMAB vs TRASTUZUMAB-DKST
TRASTUZUMAB vs TRASTUZUMAB-DTTB
TRASTUZUMAB vs TRASTUZUMAB EMTANSINE