Does TRASTUZUMAB Cause Hepatomegaly? 40 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 40 reports of Hepatomegaly have been filed in association with TRASTUZUMAB (Trazimera). This represents 0.1% of all adverse event reports for TRASTUZUMAB.
40
Reports of Hepatomegaly with TRASTUZUMAB
0.1%
of all TRASTUZUMAB reports
13
Deaths
9
Hospitalizations
How Dangerous Is Hepatomegaly From TRASTUZUMAB?
Of the 40 reports, 13 (32.5%) resulted in death, 9 (22.5%) required hospitalization.
Is Hepatomegaly Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TRASTUZUMAB. However, 40 reports have been filed with the FAERS database.
What Other Side Effects Does TRASTUZUMAB Cause?
Diarrhoea (4,996)
Off label use (3,802)
Nausea (3,499)
Fatigue (3,417)
Myelosuppression (2,552)
Disease progression (2,449)
Death (2,378)
Vomiting (2,244)
Dyspnoea (2,010)
Pyrexia (1,886)
What Other Drugs Cause Hepatomegaly?
METHOTREXATE (276)
ADALIMUMAB (225)
RUXOLITINIB (213)
CYCLOPHOSPHAMIDE (170)
VINCRISTINE (136)
ACETAMINOPHEN (126)
RITUXIMAB (115)
DEXAMETHASONE (104)
PREDNISONE (101)
SECUKINUMAB (90)
Which TRASTUZUMAB Alternatives Have Lower Hepatomegaly Risk?
TRASTUZUMAB vs TRASTUZUMAB-ANNS
TRASTUZUMAB vs TRASTUZUMAB DERUXTECAN
TRASTUZUMAB vs TRASTUZUMAB-DKST
TRASTUZUMAB vs TRASTUZUMAB-DTTB
TRASTUZUMAB vs TRASTUZUMAB EMTANSINE