Does TRETINOIN Cause Synovitis? 128 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 128 reports of Synovitis have been filed in association with TRETINOIN (Tretinoin). This represents 3.1% of all adverse event reports for TRETINOIN.
128
Reports of Synovitis with TRETINOIN
3.1%
of all TRETINOIN reports
124
Deaths
88
Hospitalizations
How Dangerous Is Synovitis From TRETINOIN?
Of the 128 reports, 124 (96.9%) resulted in death, 88 (68.8%) required hospitalization, and 88 (68.8%) were considered life-threatening.
Is Synovitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TRETINOIN. However, 128 reports have been filed with the FAERS database.
What Other Side Effects Does TRETINOIN Cause?
Off label use (665)
Drug ineffective (537)
Product use in unapproved indication (466)
Vomiting (286)
Paraesthesia (284)
Pain (270)
Drug intolerance (263)
Maternal exposure during pregnancy (261)
Taste disorder (258)
Differentiation syndrome (251)
What Other Drugs Cause Synovitis?
METHOTREXATE (11,451)
ADALIMUMAB (9,965)
ABATACEPT (9,783)
ETANERCEPT (9,599)
TOCILIZUMAB (9,428)
HYDROXYCHLOROQUINE (9,123)
LEFLUNOMIDE (8,889)
RITUXIMAB (7,956)
INFLIXIMAB (7,856)
SULFASALAZINE (7,566)
Which TRETINOIN Alternatives Have Lower Synovitis Risk?
TRETINOIN vs TRIAMCINOLONE
TRETINOIN vs TRIAMCINOLONE ACETONIDE
TRETINOIN vs TRIAMCINOLONE HEXACETONIDE
TRETINOIN vs TRIAMTERENE
TRETINOIN vs TRIATEC