Does VALPROATE Cause Toxic epidermal necrolysis? 71 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 71 reports of Toxic epidermal necrolysis have been filed in association with VALPROATE (Valproate Sodium). This represents 0.5% of all adverse event reports for VALPROATE.
71
Reports of Toxic epidermal necrolysis with VALPROATE
0.5%
of all VALPROATE reports
17
Deaths
60
Hospitalizations
How Dangerous Is Toxic epidermal necrolysis From VALPROATE?
Of the 71 reports, 17 (23.9%) resulted in death, 60 (84.5%) required hospitalization, and 21 (29.6%) were considered life-threatening.
Is Toxic epidermal necrolysis Listed in the Official Label?
Yes, Toxic epidermal necrolysis is listed as a known adverse reaction in the official FDA drug label for VALPROATE.
What Other Side Effects Does VALPROATE Cause?
Foetal exposure during pregnancy (1,982)
Drug ineffective (1,268)
Seizure (1,083)
Epilepsy (878)
Somnolence (843)
Off label use (744)
Drug abuse (705)
Sopor (577)
Dysmorphism (552)
Drug interaction (513)
What Other Drugs Cause Toxic epidermal necrolysis?
ACETAMINOPHEN (980)
LAMOTRIGINE (941)
ALLOPURINOL (858)
IBUPROFEN (764)
SULFAMETHOXAZOLE\TRIMETHOPRIM (592)
CIPROFLOXACIN (576)
FUROSEMIDE (521)
VANCOMYCIN (515)
PIPERACILLIN\TAZOBACTAM (490)
PEMBROLIZUMAB (444)
Which VALPROATE Alternatives Have Lower Toxic epidermal necrolysis Risk?
VALPROATE vs VALPROIC ACID
VALPROATE vs VALPROMIDE
VALPROATE vs VALSARTAN
VALPROATE vs VALTREX
VALPROATE vs VAMOROLONE