Does VALPROIC ACID Cause Bone marrow failure? 22 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 22 reports of Bone marrow failure have been filed in association with VALPROIC ACID (Valproic Acid). This represents 0.1% of all adverse event reports for VALPROIC ACID.
22
Reports of Bone marrow failure with VALPROIC ACID
0.1%
of all VALPROIC ACID reports
5
Deaths
17
Hospitalizations
How Dangerous Is Bone marrow failure From VALPROIC ACID?
Of the 22 reports, 5 (22.7%) resulted in death, 17 (77.3%) required hospitalization, and 5 (22.7%) were considered life-threatening.
Is Bone marrow failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for VALPROIC ACID. However, 22 reports have been filed with the FAERS database.
What Other Side Effects Does VALPROIC ACID Cause?
Drug ineffective (3,511)
Drug interaction (1,542)
Toxicity to various agents (1,517)
Off label use (1,503)
Seizure (1,335)
Foetal exposure during pregnancy (1,046)
Somnolence (831)
Completed suicide (723)
Overdose (691)
Condition aggravated (673)
What Other Drugs Cause Bone marrow failure?
CYCLOPHOSPHAMIDE (1,834)
METHOTREXATE (1,401)
ETOPOSIDE (1,081)
RITUXIMAB (1,060)
CYTARABINE (1,052)
VINCRISTINE (1,001)
DOXORUBICIN (1,000)
PALBOCICLIB (951)
CARBOPLATIN (855)
BEVACIZUMAB (835)
Which VALPROIC ACID Alternatives Have Lower Bone marrow failure Risk?
VALPROIC ACID vs VALPROMIDE
VALPROIC ACID vs VALSARTAN
VALPROIC ACID vs VALTREX
VALPROIC ACID vs VAMOROLONE
VALPROIC ACID vs VANCOMYCIN