Does VALPROIC ACID Cause Encephalitis? 34 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 34 reports of Encephalitis have been filed in association with VALPROIC ACID (Valproic Acid). This represents 0.2% of all adverse event reports for VALPROIC ACID.
34
Reports of Encephalitis with VALPROIC ACID
0.2%
of all VALPROIC ACID reports
21
Deaths
31
Hospitalizations
How Dangerous Is Encephalitis From VALPROIC ACID?
Of the 34 reports, 21 (61.8%) resulted in death, 31 (91.2%) required hospitalization, and 26 (76.5%) were considered life-threatening.
Is Encephalitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for VALPROIC ACID. However, 34 reports have been filed with the FAERS database.
What Other Side Effects Does VALPROIC ACID Cause?
Drug ineffective (3,511)
Drug interaction (1,542)
Toxicity to various agents (1,517)
Off label use (1,503)
Seizure (1,335)
Foetal exposure during pregnancy (1,046)
Somnolence (831)
Completed suicide (723)
Overdose (691)
Condition aggravated (673)
What Other Drugs Cause Encephalitis?
NIVOLUMAB (377)
METHOTREXATE (372)
PREDNISONE (365)
PEMBROLIZUMAB (352)
RITUXIMAB (263)
TACROLIMUS (253)
CYCLOPHOSPHAMIDE (244)
ATEZOLIZUMAB (236)
MYCOPHENOLATE MOFETIL (228)
PREDNISOLONE (190)
Which VALPROIC ACID Alternatives Have Lower Encephalitis Risk?
VALPROIC ACID vs VALPROMIDE
VALPROIC ACID vs VALSARTAN
VALPROIC ACID vs VALTREX
VALPROIC ACID vs VAMOROLONE
VALPROIC ACID vs VANCOMYCIN