Does VALPROIC ACID Cause Propofol infusion syndrome? 45 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 45 reports of Propofol infusion syndrome have been filed in association with VALPROIC ACID (Valproic Acid). This represents 0.2% of all adverse event reports for VALPROIC ACID.
45
Reports of Propofol infusion syndrome with VALPROIC ACID
0.2%
of all VALPROIC ACID reports
36
Deaths
32
Hospitalizations
How Dangerous Is Propofol infusion syndrome From VALPROIC ACID?
Of the 45 reports, 36 (80.0%) resulted in death, 32 (71.1%) required hospitalization, and 24 (53.3%) were considered life-threatening.
Is Propofol infusion syndrome Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for VALPROIC ACID. However, 45 reports have been filed with the FAERS database.
What Other Side Effects Does VALPROIC ACID Cause?
Drug ineffective (3,511)
Drug interaction (1,542)
Toxicity to various agents (1,517)
Off label use (1,503)
Seizure (1,335)
Foetal exposure during pregnancy (1,046)
Somnolence (831)
Completed suicide (723)
Overdose (691)
Condition aggravated (673)
What Other Drugs Cause Propofol infusion syndrome?
PROPOFOL (420)
LEVETIRACETAM (60)
MIDAZOLAM (58)
DEXAMETHASONE (51)
LACOSAMIDE (50)
KETAMINE (43)
TOPIRAMATE (39)
CLOBAZAM (36)
PENTOBARBITAL (36)
ISOFLURANE (35)
Which VALPROIC ACID Alternatives Have Lower Propofol infusion syndrome Risk?
VALPROIC ACID vs VALPROMIDE
VALPROIC ACID vs VALSARTAN
VALPROIC ACID vs VALTREX
VALPROIC ACID vs VAMOROLONE
VALPROIC ACID vs VANCOMYCIN