Does ISOFLURANE Cause Propofol infusion syndrome? 35 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 35 reports of Propofol infusion syndrome have been filed in association with ISOFLURANE (Isoflurane). This represents 4.2% of all adverse event reports for ISOFLURANE.
35
Reports of Propofol infusion syndrome with ISOFLURANE
4.2%
of all ISOFLURANE reports
34
Deaths
26
Hospitalizations
How Dangerous Is Propofol infusion syndrome From ISOFLURANE?
Of the 35 reports, 34 (97.1%) resulted in death, 26 (74.3%) required hospitalization, and 22 (62.9%) were considered life-threatening.
Is Propofol infusion syndrome Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ISOFLURANE. However, 35 reports have been filed with the FAERS database.
What Other Side Effects Does ISOFLURANE Cause?
Drug ineffective (134)
Hypotension (127)
Off label use (90)
Hyperthermia malignant (87)
Intestinal ischaemia (77)
Status epilepticus (75)
Systemic inflammatory response syndrome (63)
Necrosis ischaemic (56)
Post procedural complication (55)
Metabolic acidosis (54)
What Other Drugs Cause Propofol infusion syndrome?
PROPOFOL (420)
LEVETIRACETAM (60)
MIDAZOLAM (58)
DEXAMETHASONE (51)
LACOSAMIDE (50)
VALPROIC ACID (45)
KETAMINE (43)
TOPIRAMATE (39)
CLOBAZAM (36)
PENTOBARBITAL (36)
Which ISOFLURANE Alternatives Have Lower Propofol infusion syndrome Risk?
ISOFLURANE vs ISONIAZID
ISOFLURANE vs ISONIAZID\PYRAZINAMIDE\RIFAMPIN
ISOFLURANE vs ISONIAZID\PYRIDOXINE\SULFAMETHOXAZOLE\TRIMETHOPRIM
ISOFLURANE vs ISONIAZID\RIFAMPIN
ISOFLURANE vs ISOPROPANOLAMINE