Does VALPROIC ACID Cause Serotonin syndrome? 152 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 152 reports of Serotonin syndrome have been filed in association with VALPROIC ACID (Valproic Acid). This represents 0.8% of all adverse event reports for VALPROIC ACID.
152
Reports of Serotonin syndrome with VALPROIC ACID
0.8%
of all VALPROIC ACID reports
8
Deaths
107
Hospitalizations
How Dangerous Is Serotonin syndrome From VALPROIC ACID?
Of the 152 reports, 8 (5.3%) resulted in death, 107 (70.4%) required hospitalization, and 25 (16.4%) were considered life-threatening.
Is Serotonin syndrome Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for VALPROIC ACID. However, 152 reports have been filed with the FAERS database.
What Other Side Effects Does VALPROIC ACID Cause?
Drug ineffective (3,511)
Drug interaction (1,542)
Toxicity to various agents (1,517)
Off label use (1,503)
Seizure (1,335)
Foetal exposure during pregnancy (1,046)
Somnolence (831)
Completed suicide (723)
Overdose (691)
Condition aggravated (673)
What Other Drugs Cause Serotonin syndrome?
VENLAFAXINE (1,632)
SERTRALINE (1,563)
FLUOXETINE (1,457)
DULOXETINE (1,352)
TRAMADOL (1,229)
BUPROPION (1,058)
ESCITALOPRAM OXALATE (1,051)
QUETIAPINE (947)
TRAZODONE (831)
FENTANYL (778)
Which VALPROIC ACID Alternatives Have Lower Serotonin syndrome Risk?
VALPROIC ACID vs VALPROMIDE
VALPROIC ACID vs VALSARTAN
VALPROIC ACID vs VALTREX
VALPROIC ACID vs VAMOROLONE
VALPROIC ACID vs VANCOMYCIN