Does VEMURAFENIB Cause Immune-mediated hepatitis? 8 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 8 reports of Immune-mediated hepatitis have been filed in association with VEMURAFENIB (ZELBORAF). This represents 0.1% of all adverse event reports for VEMURAFENIB.
8
Reports of Immune-mediated hepatitis with VEMURAFENIB
0.1%
of all VEMURAFENIB reports
0
Deaths
6
Hospitalizations
How Dangerous Is Immune-mediated hepatitis From VEMURAFENIB?
Of the 8 reports, 6 (75.0%) required hospitalization, and 1 (12.5%) were considered life-threatening.
Is Immune-mediated hepatitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for VEMURAFENIB. However, 8 reports have been filed with the FAERS database.
What Other Side Effects Does VEMURAFENIB Cause?
Rash (1,202)
Arthralgia (783)
Off label use (782)
Fatigue (773)
Diarrhoea (655)
Nausea (601)
Pyrexia (569)
Death (505)
Alopecia (445)
Decreased appetite (383)
What Other Drugs Cause Immune-mediated hepatitis?
NIVOLUMAB (640)
PEMBROLIZUMAB (549)
IPILIMUMAB (443)
CARBOPLATIN (213)
PACLITAXEL (167)
ATEZOLIZUMAB (142)
BEVACIZUMAB (108)
DURVALUMAB (90)
LENVATINIB (86)
PEMETREXED (86)
Which VEMURAFENIB Alternatives Have Lower Immune-mediated hepatitis Risk?
VEMURAFENIB vs VENETOCLAX
VEMURAFENIB vs VENLAFAXINE
VEMURAFENIB vs VENTAVIS
VEMURAFENIB vs VENTOLIN
VEMURAFENIB vs VENTOLIN HFA