Immune-mediated hepatitis: Which Medications Cause It? (1,615 Reports Across 72 Drugs)
Boost Your Natural Energy & Metabolism
Mitolyn — 6 exotic plants to unlock your body's fat-burning power. 90-day guarantee.
Immune-mediated hepatitis has been reported as an adverse event with 72 different drugs in the FDA's FAERS database, with 1,615 total reports. 270 of these reports resulted in death.The drugs most commonly associated with Immune-mediated hepatitis are NIVOLUMAB, PEMBROLIZUMAB, and IPILIMUMAB.
1,615
Total Reports
72
Drugs Involved
270
Deaths
894
Hospitalizations
61.5 yrs
Average Patient Age
42.7% / 57.3%
Female / Male
Which Drugs Cause Immune-mediated hepatitis Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| NIVOLUMAB | 640 | 0.7% | 94 | 360 | 95 |
| PEMBROLIZUMAB | 549 | 0.7% | 101 | 318 | 66 |
| IPILIMUMAB | 443 | 1.2% | 58 | 258 | 65 |
| CARBOPLATIN | 213 | 0.3% | 32 | 124 | 38 |
| PACLITAXEL | 167 | 0.2% | 25 | 89 | 21 |
| ATEZOLIZUMAB | 142 | 0.4% | 28 | 59 | 8 |
| BEVACIZUMAB | 108 | 0.1% | 27 | 44 | 13 |
| DURVALUMAB | 90 | 0.5% | 13 | 42 | 10 |
| LENVATINIB | 86 | 0.3% | 11 | 58 | 6 |
| PEMETREXED | 86 | 0.4% | 7 | 52 | 18 |
| TREMELIMUMAB | 51 | 2.1% | 6 | 22 | 3 |
| GEMCITABINE | 43 | 0.1% | 2 | 15 | 5 |
| CABOZANTINIB | 38 | 1.0% | 3 | 33 | 9 |
| OXALIPLATIN | 31 | 0.1% | 7 | 20 | 4 |
| METHYLPREDNISOLONE | 30 | 0.1% | 10 | 13 | 5 |
| MYCOPHENOLATE MOFETIL | 23 | 0.0% | 6 | 18 | 9 |
| PREDNISONE | 23 | 0.0% | 3 | 15 | 1 |
| FLUOROURACIL | 20 | 0.0% | 5 | 13 | 3 |
| TISLELIZUMAB | 20 | 0.4% | 3 | 12 | 3 |
| CABOZANTINIB S-MALATE | 19 | 0.1% | 1 | 4 | 1 |