Does VINCRISTINE Cause Cholestasis? 273 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 273 reports of Cholestasis have been filed in association with VINCRISTINE (VinCRIStine Sulfate). This represents 0.4% of all adverse event reports for VINCRISTINE.
273
Reports of Cholestasis with VINCRISTINE
0.4%
of all VINCRISTINE reports
12
Deaths
112
Hospitalizations
How Dangerous Is Cholestasis From VINCRISTINE?
Of the 273 reports, 12 (4.4%) resulted in death, 112 (41.0%) required hospitalization, and 24 (8.8%) were considered life-threatening.
Is Cholestasis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for VINCRISTINE. However, 273 reports have been filed with the FAERS database.
What Other Side Effects Does VINCRISTINE Cause?
Febrile neutropenia (8,676)
Off label use (6,562)
Disease progression (5,252)
Neutropenia (4,982)
Drug ineffective (4,084)
Pyrexia (3,460)
Product use in unapproved indication (3,073)
Thrombocytopenia (2,940)
Sepsis (2,791)
Anaemia (2,603)
What Other Drugs Cause Cholestasis?
ACETAMINOPHEN (1,269)
ATORVASTATIN (898)
PANTOPRAZOLE (535)
METHOTREXATE (507)
AMOXICILLIN\CLAVULANATE (480)
SULFAMETHOXAZOLE\TRIMETHOPRIM (462)
ENOXAPARIN (404)
PIPERACILLIN\TAZOBACTAM (394)
ESOMEPRAZOLE (363)
NIVOLUMAB (342)
Which VINCRISTINE Alternatives Have Lower Cholestasis Risk?
VINCRISTINE vs VINDESINE
VINCRISTINE vs VINORELBINE
VINCRISTINE vs VINORELBINE\VINORELBINE
VINCRISTINE vs VIREAD
VINCRISTINE vs VISIPAQUE