Does VORINOSTAT Cause Constipation? 21 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 21 reports of Constipation have been filed in association with VORINOSTAT (ZOLINZA). This represents 1.7% of all adverse event reports for VORINOSTAT.
21
Reports of Constipation with VORINOSTAT
1.7%
of all VORINOSTAT reports
5
Deaths
12
Hospitalizations
How Dangerous Is Constipation From VORINOSTAT?
Of the 21 reports, 5 (23.8%) resulted in death, 12 (57.1%) required hospitalization, and 4 (19.0%) were considered life-threatening.
Is Constipation Listed in the Official Label?
Yes, Constipation is listed as a known adverse reaction in the official FDA drug label for VORINOSTAT.
What Other Side Effects Does VORINOSTAT Cause?
Febrile neutropenia (177)
Product use in unapproved indication (122)
Thrombocytopenia (89)
Off label use (88)
Anaemia (79)
Sepsis (77)
Diarrhoea (68)
Neutropenia (63)
Nausea (61)
Fatigue (59)
What Other Drugs Cause Constipation?
LENALIDOMIDE (9,635)
NIRAPARIB (4,128)
ADALIMUMAB (4,063)
SEMAGLUTIDE (4,036)
TIRZEPATIDE (3,417)
ERENUMAB-AOOE (3,104)
MORPHINE (2,979)
OXYCODONE (2,747)
PALBOCICLIB (2,705)
POMALIDOMIDE (2,374)
Which VORINOSTAT Alternatives Have Lower Constipation Risk?
VORINOSTAT vs VORTIOXETINE
VORINOSTAT vs VORTIOXETINE HYDROBROMIDE
VORINOSTAT vs VOSORITIDE
VORINOSTAT vs VOTRIENT
VORINOSTAT vs VOXELOTOR