Does VORINOSTAT Cause Haematotoxicity? 16 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 16 reports of Haematotoxicity have been filed in association with VORINOSTAT (ZOLINZA). This represents 1.3% of all adverse event reports for VORINOSTAT.
16
Reports of Haematotoxicity with VORINOSTAT
1.3%
of all VORINOSTAT reports
2
Deaths
0
Hospitalizations
How Dangerous Is Haematotoxicity From VORINOSTAT?
Of the 16 reports, 2 (12.5%) resulted in death, and 10 (62.5%) were considered life-threatening.
Is Haematotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for VORINOSTAT. However, 16 reports have been filed with the FAERS database.
What Other Side Effects Does VORINOSTAT Cause?
Febrile neutropenia (177)
Product use in unapproved indication (122)
Thrombocytopenia (89)
Off label use (88)
Anaemia (79)
Sepsis (77)
Diarrhoea (68)
Neutropenia (63)
Nausea (61)
Fatigue (59)
What Other Drugs Cause Haematotoxicity?
CYCLOPHOSPHAMIDE (1,410)
DOXORUBICIN (1,180)
VINCRISTINE (1,038)
RITUXIMAB (812)
CARBOPLATIN (803)
METHOTREXATE (799)
PREDNISONE (730)
CYTARABINE (701)
ETOPOSIDE (677)
CISPLATIN (668)
Which VORINOSTAT Alternatives Have Lower Haematotoxicity Risk?
VORINOSTAT vs VORTIOXETINE
VORINOSTAT vs VORTIOXETINE HYDROBROMIDE
VORINOSTAT vs VOSORITIDE
VORINOSTAT vs VOTRIENT
VORINOSTAT vs VOXELOTOR