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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Parkinsonism: Which Medications Are Safest? (132 Drugs Compared)

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132 medications are used for Parkinsonism, with 1,867 combined adverse event reports. The most reported drugs for Parkinsonism are CARBIDOPA\LEVODOPA and TROPATEPINE.

1,867
Total Reports
132
Drugs Used

All Medications for Parkinsonism Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
CARBIDOPA\LEVODOPA - 368 12,844 25,836 22.0%
TROPATEPINE - 233 290 831 19.9%
PIMAVANSERIN pimavanserin 209 12,352 7,471 26.7%
ROPINIROLE ropinirole hydrochloride 136 310 1,192 7.3%
PRAMIPEXOLE Pramipexole Dihydrochloride 126 327 2,091 5.4%
TRIHEXYPHENIDYL Trihexyphenidyl Hydrochloride 120 334 927 18.7%
BENSERAZIDE\LEVODOPA - 113 131 1,153 6.5%
AMANTADINE Amantadine 71 483 1,579 9.4%
ROTIGOTINE Neupro 67 1,299 1,727 16.6%
CARBIDOPA\ENTACAPONE\LEVODOPA - 66 298 904 12.6%
BIPERIDEN - 61 180 1,008 10.0%
LEVODOPA L-Dopa 59 546 729 8.3%
RASAGILINE Rasagiline 58 255 961 9.3%
ZONISAMIDE Zonisamide 41 299 1,424 6.3%
IODINE\IOFLUPANE I-123 - 38 7 15 1.6%
ENTACAPONE Entacapone 36 109 557 7.7%
DROXIDOPA Droxidopa 33 2,500 2,900 12.4%
RIVASTIGMINE Exelon 30 2,232 2,716 24.5%
APOMORPHINE apomorphine hydrocloride 28 372 1,002 4.7%
ISTRADEFYLLINE NOURIANZ 24 716 511 14.3%

View all 132 drugs →

Most Reported Drugs for Parkinsonism

#1 most reported
#2 most reported
#3 most reported