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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

All Drugs Associated with Breakthrough pain

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70 drugs have been associated with Breakthrough pain in FAERS reports.

Drug Reports Deaths Hosp. Life-Threat.
FENTANYL 259 5 21 0
BUPRENORPHINE 184 2 5 2
OXYCODONE 105 12 13 2
MORPHINE 59 9 16 0
SECUKINUMAB 59 0 2 0
ETANERCEPT 57 0 1 0
ADALIMUMAB 51 0 0 0
PREGABALIN 48 0 8 0
TOFACITINIB 47 0 3 0
HYDROCODONE 46 0 1 0
GABAPENTIN 39 0 4 0
TAPENTADOL 35 0 3 0
CERTOLIZUMAB PEGOL 27 0 0 0
METHOTREXATE 27 0 15 0
CYCLOPHOSPHAMIDE 25 0 15 0
ACETAMINOPHEN\HYDROCODONE 23 1 5 0
PREDNISONE 23 0 17 0
HYDROMORPHONE 22 2 8 1
ACETAMINOPHEN\OXYCODONE 20 2 4 0
BACLOFEN 20 0 2 0
TRAMADOL 18 6 4 0
DULOXETINE 17 0 3 0
OXYCONTIN 17 2 0 0
DURAGESIC 16 0 4 0
UPADACITINIB 16 0 2 0
VINCRISTINE 16 1 15 0
BUPRENORPHINE\NALOXONE 15 1 5 0
CYTARABINE 15 1 15 0
BUPIVACAINE 14 0 0 0
HYDROCORTISONE 14 0 14 0
INFLIXIMAB 14 0 0 0
MERCAPTOPURINE 14 0 14 0
ASPARAGINASE ERWINIA CHRYSANTHEMI 13 0 13 0
DAUNORUBICIN 13 0 13 0
DEXAMETHASONE 13 0 13 0
DOCETAXEL 13 1 1 0
DOXORUBICIN 13 0 12 0
LEUPROLIDE 13 1 0 0
OCTREOTIDE 13 2 7 2
PEGASPARGASE 13 0 13 0
SODIUM OXYBATE 13 0 3 0
ENZALUTAMIDE 12 0 0 0
BICALUTAMIDE 10 0 0 0
METFORMIN 10 0 0 0
USTEKINUMAB 10 0 0 0
VALSARTAN 10 0 0 0
ZOLPIDEM 10 5 0 0
ABATACEPT 9 0 0 0
CLONIDINE 9 0 0 0
GOLIMUMAB 9 0 0 0
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