Does METHOTREXATE Cause Breakthrough pain? 27 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 27 reports of Breakthrough pain have been filed in association with METHOTREXATE (Methotrexate). This represents 0.0% of all adverse event reports for METHOTREXATE.
27
Reports of Breakthrough pain with METHOTREXATE
0.0%
of all METHOTREXATE reports
0
Deaths
15
Hospitalizations
How Dangerous Is Breakthrough pain From METHOTREXATE?
Of the 27 reports, 15 (55.6%) required hospitalization.
Is Breakthrough pain Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 27 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Breakthrough pain?
FENTANYL (259)
BUPRENORPHINE (184)
OXYCODONE (105)
MORPHINE (59)
SECUKINUMAB (59)
ETANERCEPT (57)
ADALIMUMAB (51)
PREGABALIN (48)
TOFACITINIB (47)
HYDROCODONE (46)
Which METHOTREXATE Alternatives Have Lower Breakthrough pain Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA