Anthracycline Topoisomerase Inhibitor [EPC]: Side Effects & Safety Data for 4 Drugs
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Anthracycline Topoisomerase Inhibitor [EPC] includes 4 drugs with a combined 113,918 adverse event reports in the FDA FAERS database. Compare their safety profiles, side effects, and outcomes below.
4
Drugs in Class
113,918
Combined Reports
All Anthracycline Topoisomerase Inhibitor [EPC] Drugs Ranked by Reports
| Drug | Brand Name | Reports | Deaths | Hosp. | Death Rate |
|---|---|---|---|---|---|
| DOXORUBICIN | Doxorubicin Hydrochloride | 82,754 | 15,653 | 28,630 | 18.9% |
| EPIRUBICIN | Ellence | 16,274 | 2,212 | 5,603 | 13.6% |
| DAUNORUBICIN | Daunorubicin Hydrochloride | 9,852 | 2,263 | 4,248 | 23.0% |
| IDARUBICIN | Idamycin PFS | 5,038 | 1,260 | 1,856 | 25.0% |
Common Side Effects in Anthracycline Topoisomerase Inhibitor [EPC] Drugs
| Side Effect | Reports | Deaths |
|---|---|---|
| Febrile neutropenia | 11,722 | 1,449 |
| Off label use | 9,312 | 2,053 |
| Neutropenia | 7,831 | 1,208 |
| Disease progression | 6,894 | 1,639 |
| Drug ineffective | 5,627 | 1,677 |
| Pyrexia | 5,384 | 722 |
| Thrombocytopenia | 4,719 | 864 |
| Anaemia | 4,487 | 658 |
| Nausea | 4,472 | 400 |
| Product use in unapproved indication | 4,098 | 982 |