Direct Thrombin Inhibitor [EPC]: Side Effects & Safety Data for 3 Drugs
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Direct Thrombin Inhibitor [EPC] includes 3 drugs with a combined 38,613 adverse event reports in the FDA FAERS database. Compare their safety profiles, side effects, and outcomes below.
3
Drugs in Class
38,613
Combined Reports
All Direct Thrombin Inhibitor [EPC] Drugs Ranked by Reports
| Drug | Brand Name | Reports | Deaths | Hosp. | Death Rate |
|---|---|---|---|---|---|
| DABIGATRAN ETEXILATE | dabigatran etexilate | 37,091 | 5,806 | 21,235 | 15.7% |
| BIVALIRUDIN | BIVALIRUDIN | 839 | 137 | 249 | 16.3% |
| ARGATROBAN | Argatroban | 683 | 147 | 281 | 21.5% |
Common Side Effects in Direct Thrombin Inhibitor [EPC] Drugs
| Side Effect | Reports | Deaths |
|---|---|---|
| Gastrointestinal haemorrhage | 4,141 | 1,022 |
| Cerebrovascular accident | 2,180 | 217 |
| Fall | 1,786 | 315 |
| Ischaemic stroke | 1,594 | 151 |
| Haemorrhage | 1,448 | 423 |
| Anaemia | 1,438 | 244 |
| Death | 1,052 | 1,052 |
| Cerebral haemorrhage | 977 | 497 |
| Rectal haemorrhage | 973 | 201 |
| Off label use | 968 | 92 |