Direct Thrombin Inhibitor [EPC] — Common Side Effects
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| Side Effect | Total Reports | Drugs | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| Gastrointestinal haemorrhage | 4,141 | 3 | 1,022 | 3,632 | 297 |
| Cerebrovascular accident | 2,180 | 2 | 217 | 1,192 | 160 |
| Fall | 1,786 | 1 | 315 | 1,312 | 218 |
| Ischaemic stroke | 1,594 | 3 | 151 | 1,059 | 231 |
| Haemorrhage | 1,448 | 3 | 423 | 767 | 173 |
| Anaemia | 1,438 | 3 | 244 | 1,255 | 123 |
| Death | 1,052 | 3 | 1,052 | 295 | 49 |
| Cerebral haemorrhage | 977 | 3 | 497 | 644 | 192 |
| Rectal haemorrhage | 973 | 2 | 201 | 757 | 78 |
| Off label use | 968 | 3 | 92 | 390 | 81 |
| Drug ineffective | 868 | 3 | 68 | 520 | 133 |
| Atrial fibrillation | 864 | 2 | 80 | 543 | 32 |
| Upper gastrointestinal haemorrhage | 861 | 1 | 205 | 794 | 75 |
| Acute kidney injury | 818 | 3 | 220 | 664 | 143 |
| Lower gastrointestinal haemorrhage | 757 | 1 | 141 | 702 | 53 |
| Cerebral infarction | 748 | 2 | 94 | 437 | 99 |
| Coagulopathy | 747 | 3 | 232 | 644 | 91 |
| Procoagulant therapy | 737 | 1 | 4 | 621 | 4 |
| Haemorrhage intracranial | 725 | 3 | 338 | 516 | 140 |
| Haemorrhagic anaemia | 718 | 1 | 103 | 701 | 28 |
| Melaena | 710 | 2 | 150 | 593 | 101 |
| Dyspnoea | 703 | 2 | 87 | 460 | 61 |
| Haematuria | 702 | 1 | 115 | 559 | 52 |
| Subdural haematoma | 656 | 2 | 153 | 535 | 128 |
| Asthenia | 586 | 1 | 59 | 354 | 44 |
| Pulmonary embolism | 572 | 3 | 99 | 340 | 78 |
| Pneumonia | 569 | 3 | 208 | 454 | 63 |
| Dizziness | 562 | 1 | 33 | 234 | 28 |
| Epistaxis | 551 | 3 | 112 | 363 | 56 |
| Hypotension | 537 | 3 | 138 | 434 | 97 |