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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Acute kidney injury: Which Medications Cause It? (141,842 Reports Across 1,717 Drugs)

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Acute kidney injury has been reported as an adverse event with 1,717 different drugs in the FDA's FAERS database, with 141,842 total reports. 21,563 of these reports resulted in death.The drugs most commonly associated with Acute kidney injury are OMEPRAZOLE, ESOMEPRAZOLE, and LANSOPRAZOLE.

141,842
Total Reports
1,717
Drugs Involved
21,563
Deaths
90,864
Hospitalizations
61.6 yrs
Average Patient Age
46.1% / 53.9%
Female / Male

Which Drugs Cause Acute kidney injury Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
OMEPRAZOLE 19,260 22.1% 2,599 3,523 256
ESOMEPRAZOLE 18,678 24.7% 2,504 3,371 237
LANSOPRAZOLE 16,359 26.9% 2,355 2,304 67
PANTOPRAZOLE 15,961 20.3% 2,372 2,908 264
METFORMIN 11,361 12.5% 1,267 8,814 3,497
FUROSEMIDE 7,984 15.4% 656 6,254 1,072
DEXLANSOPRAZOLE 7,599 31.7% 1,018 756 5
VANCOMYCIN 4,018 11.9% 469 2,563 481
TACROLIMUS 4,005 4.4% 669 2,772 631
RIVAROXABAN 3,735 2.9% 1,219 3,473 278
IBUPROFEN 3,639 4.2% 273 2,923 649
METHOTREXATE 3,409 1.3% 682 2,249 697
RAMIPRIL 3,286 9.9% 209 2,788 532
SPIRONOLACTONE 3,273 15.6% 256 2,669 507
ACETAMINOPHEN 3,132 2.3% 822 2,027 735
ASPIRIN 2,976 3.2% 766 2,680 367
AMLODIPINE 2,721 4.2% 455 2,043 772
PREDNISONE 2,709 1.7% 623 1,942 510
DEXAMETHASONE 2,657 2.1% 733 1,911 509
RABEPRAZOLE 2,545 22.3% 601 260 3

View all 1,717 drugs →

Top 3 Drugs Associated With Acute kidney injury

19,260 reports
18,678 reports
16,359 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)