Phosphodiesterase 4 Inhibitor [EPC]: Side Effects & Safety Data for 4 Drugs
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Phosphodiesterase 4 Inhibitor [EPC] includes 4 drugs with a combined 147,607 adverse event reports in the FDA FAERS database. Compare their safety profiles, side effects, and outcomes below.
4
Drugs in Class
147,607
Combined Reports
All Phosphodiesterase 4 Inhibitor [EPC] Drugs Ranked by Reports
| Drug | Brand Name | Reports | Deaths | Hosp. | Death Rate |
|---|---|---|---|---|---|
| APREMILAST | Otezla | 136,713 | 4,704 | 9,544 | 3.4% |
| CRISABOROLE | Eucrisa | 7,784 | 22 | 53 | 0.3% |
| ROFLUMILAST | ROFLUMILAST | 2,700 | 645 | 625 | 23.9% |
| ENSIFENTRINE | Ohtuvayre | 410 | 2 | 77 | 0.5% |
Common Side Effects in Phosphodiesterase 4 Inhibitor [EPC] Drugs
| Side Effect | Reports | Deaths |
|---|---|---|
| Diarrhoea | 24,043 | 1,255 |
| Nausea | 21,552 | 1,069 |
| Psoriasis | 19,298 | 348 |
| Headache | 17,216 | 1,242 |
| Drug ineffective | 16,112 | 1,007 |
| Abdominal discomfort | 7,718 | 1,337 |
| Psoriatic arthropathy | 7,044 | 1,594 |
| Rash | 6,266 | 1,593 |
| Pain | 6,180 | 1,369 |
| Vomiting | 6,003 | 1,379 |