Thyroid Hormone Synthesis Inhibitor [EPC]: Side Effects & Safety Data for 2 Drugs
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Thyroid Hormone Synthesis Inhibitor [EPC] includes 2 drugs with a combined 3,450 adverse event reports in the FDA FAERS database. Compare their safety profiles, side effects, and outcomes below.
2
Drugs in Class
3,450
Combined Reports
All Thyroid Hormone Synthesis Inhibitor [EPC] Drugs Ranked by Reports
| Drug | Brand Name | Reports | Deaths | Hosp. | Death Rate |
|---|---|---|---|---|---|
| METHIMAZOLE | Methimazole | 2,500 | 185 | 1,068 | 7.4% |
| PROPYLTHIOURACIL | Propylthiouracil | 950 | 63 | 438 | 6.6% |
Common Side Effects in Thyroid Hormone Synthesis Inhibitor [EPC] Drugs
| Side Effect | Reports | Deaths |
|---|---|---|
| Drug ineffective | 426 | 24 |
| Agranulocytosis | 305 | 41 |
| Hyperthyroidism | 264 | 11 |
| Off label use | 197 | 6 |
| Foetal exposure during pregnancy | 195 | 10 |
| Exposure during pregnancy | 138 | 0 |
| Hypothyroidism | 120 | 3 |
| Neutropenia | 113 | 7 |
| Maternal exposure during pregnancy | 106 | 2 |
| Anti-neutrophil cytoplasmic antibody positive vasculitis | 105 | 13 |