Does ACETAMINOPHEN Cause Acute hepatic failure? 3,141 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 3,141 reports of Acute hepatic failure have been filed in association with ACETAMINOPHEN (Hydrocodone Bitartrate and Acetaminophen). This represents 2.3% of all adverse event reports for ACETAMINOPHEN.
3,141
Reports of Acute hepatic failure with ACETAMINOPHEN
2.3%
of all ACETAMINOPHEN reports
852
Deaths
2,451
Hospitalizations
How Dangerous Is Acute hepatic failure From ACETAMINOPHEN?
Of the 3,141 reports, 852 (27.1%) resulted in death, 2,451 (78.0%) required hospitalization, and 757 (24.1%) were considered life-threatening.
Is Acute hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ACETAMINOPHEN. However, 3,141 reports have been filed with the FAERS database.
What Other Side Effects Does ACETAMINOPHEN Cause?
Drug ineffective (17,522)
Toxicity to various agents (16,128)
Off label use (9,410)
Vomiting (9,055)
Pain (8,573)
Fatigue (8,202)
Overdose (7,917)
Nausea (7,245)
Rash (7,107)
Headache (7,084)
What Other Drugs Cause Acute hepatic failure?
PREDNISONE (439)
IBUPROFEN (412)
RITUXIMAB (412)
CYCLOPHOSPHAMIDE (411)
DOXORUBICIN (385)
VINCRISTINE (346)
PREDNISOLONE (301)
METHOTREXATE (285)
DEXAMETHASONE (249)
RIFAMPIN (210)
Which ACETAMINOPHEN Alternatives Have Lower Acute hepatic failure Risk?
ACETAMINOPHEN vs ACETAMINOPHEN AND OR DEXTROMETHORPHAN AND OR DIPHENHYDRAMINE AND OR GUAIFENESIN AND OR PHENYLEPHRINE AND OR PSEUDOEPHEDRINE
ACETAMINOPHEN vs ACETAMINOPHEN W/HYDROCODONE
ACETAMINOPHEN vs ACETAMINOPHEN\ASPIRIN\CAFFEINE
ACETAMINOPHEN vs ACETAMINOPHEN\ASPIRIN\CAFFEINE\SALICYLAMIDE
ACETAMINOPHEN vs ACETAMINOPHEN\BELLADONNA LEAF\CAFFEINE\OPIUM