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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

All Drugs Associated with Acute hepatic failure

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557 drugs have been associated with Acute hepatic failure in FAERS reports.

Drug Reports Deaths Hosp. Life-Threat.
ACETAMINOPHEN 3,141 852 2,451 757
PREDNISONE 439 285 265 74
IBUPROFEN 412 51 341 99
RITUXIMAB 412 329 203 64
CYCLOPHOSPHAMIDE 411 299 187 51
DOXORUBICIN 385 262 172 31
VINCRISTINE 346 241 178 54
PREDNISOLONE 301 181 204 52
METHOTREXATE 285 174 191 96
DEXAMETHASONE 249 182 167 53
RIFAMPIN 210 41 141 35
ISONIAZID 206 45 139 29
METHYLPREDNISOLONE 192 146 133 84
MYCOPHENOLATE MOFETIL 184 116 122 64
AMIODARONE 181 43 113 60
TACROLIMUS 175 113 117 54
PYRAZINAMIDE 170 30 117 22
ATORVASTATIN 158 65 84 26
LEVETIRACETAM 156 66 106 24
METFORMIN 156 61 102 61
AMOXICILLIN 154 63 113 55
ETOPOSIDE 148 117 102 18
ETHAMBUTOL 146 38 83 23
PACLITAXEL 139 103 96 19
CIPROFLOXACIN 134 34 109 60
ACETAMINOPHEN\HYDROCODONE 133 40 120 29
TRASTUZUMAB 124 96 79 2
BEVACIZUMAB 123 95 87 11
BLEOMYCIN 119 95 92 7
DOCETAXEL 115 92 70 1
METRONIDAZOLE 115 64 51 13
LAMOTRIGINE 108 18 85 28
PROCARBAZINE 107 94 81 14
VALPROIC ACID 99 22 69 18
ALCOHOL 98 36 87 23
PANTOPRAZOLE 93 21 46 12
NIVOLUMAB 90 63 70 28
DICLOFENAC 89 60 69 22
VENLAFAXINE 89 21 73 47
CYTARABINE 86 50 52 27
CARBOPLATIN 84 38 55 29
SULFAMETHOXAZOLE\TRIMETHOPRIM 83 48 60 24
OLANZAPINE 80 17 53 19
ACETAMINOPHEN\DIPHENHYDRAMINE 75 22 73 14
AMOXICILLIN\CLAVULANATE 75 30 46 20
ASPIRIN 74 40 63 12
HUMAN IMMUNOGLOBULIN G 74 53 24 11
SIMVASTATIN 73 27 36 19
ACETAMINOPHEN\CODEINE 69 36 43 27
OXALIPLATIN 69 41 30 18
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